Uprima (apomorphine hydrochloride) FAQuestions
Drug side effects, interaction, risks information & price comparisons.
What is Uprima generic (sublingual tablets) prescription drug used for?
Impotence (erectile dysfunction) in men.
How does Uprima (apomorphine hydrochloride) work?
Uprima medicine contains the active ingredient apomorphine hydrochloride, which is a type of medicine known as a dopamine agonist. It works by enhancing the nerve signals that cause an genital erection. The tablets works as fast as 10 minutes after placing under your tongue and stays effective for up to 24 hours.
An erection is produced via a complex chain of events. The process is started with sexual stimulation from sight, smell, sound or touch. This causes nerve signals to be sent from the brain to the male genital reproductive organ (penis), which in turn cause the blood vessels in the penis to relax and widen. This allows the penis to fill with blood and makes it become erect.
Apomorphine pills works by enhancing the nerve signals that are sent from the brain to the penis during sexual stimulation.
The drug does this by mimicking the action of dopamine, which is a natural chemical called a neurotransmitter. Neurotransmitters are involved in sending signals along nerves. They act on special receptor sites in the nervous system to produce their effects. Dopamine acts on receptors called dopamine receptors, and this causes nerve signals with various effects to be sent. When dopamine acts on receptors in an area of the brain called the hypothalamus, it causes the nerve signals that produce an erection to be sent to the penis.
Apomorphine drug mimics the erection-producing effect of dopamine by stimulating the same dopamine receptors in the hypothalamus. This enhances the effect of natural dopamine that is produced as a result of sexual stimulation. The nerve signals to the penis are enhanced, and this results in blood entering the penis, ultimately causing it to become rigid and erect.
As apomorphine pills enhances the action of dopamine in producing an genital erection, it will only work once sexual stimulation has occurred. It does not increase sex-drive (libido) and is not an aphrodisiac. The sublingual tablet dissolves under the tongue, where it immediately enters the bloodstream, causing an erection in most sexually stimulated men in about 20 minutes.
What are the consumer product best cheap low sale prices online?
Apomorphine generic 2mg dose – 4 tablets = $24.95
Apomorphine generic 2mg dose – 12 tablets = $69.95
Apomorphine generic 2mg dose – 20 tablets = $99.95
Apomorphine generic 2mg dose – 32 tablets = $145.00
Apomorphine generic 3mg dose – 32 tablets = $199.00 Best Value
Where can I buy Uprima generic prescription drug online?
You can order this medication at this online discount pharmacy with discreet delivery and FREE international shipping.
International Shipping & Returns
Your internet online order will be dispatched within 48 hours of receipt. The order will be shipped in a plain discreet package, with no declarations. It is the customers responsibility to ensure compliance with any customs formalities or similar in your country of residence. Experience has shown that delivery is normally within 5 – 10 working days, however some destinations may take up to 21 days due to local infrastructure.
Delivery is currently taking 5 – 21 days, from the time of order.
For health and safety reasons, we cannot accept returns. If your order was damaged during shipping, please return the goods, for prompt replacement.
How should you take this prescription drug?
There should be a minimum of eight hours between doses of this medicine.
You should drink a small amount of water before taking this medicine to help it to dissolve under the tongue. The tablet should then be placed under the tongue and allowed to dissolve. If any of the tablet remains after 20 minutes it may be swallowed.
This medicine may uncommonly cause fainting. People normally experience warning symptoms of this, such as nausea, vomiting, pallor, sweating, hot flushes and dizziness or lightheadedness. If you experience these problem symptoms, you should not attempt to stand up – lie down and raise your legs until the symptoms pass.
This medicine may cause dizziness and lightheadedness. For this reason you should not drive or operate machinery for at least two hours after taking the medicine, or until any symptoms pass.
If this medicine is taken with alcohol there is an increased risk of a drop in blood pressure that might make you feel dizzy. In addition, alcohol can impair sexual performance.
- Use with caution in
- Decreased kidney function
- Decreased liver function
- Elderly people
- History of drops in blood pressure when moving from sitting to standing, which causes dizziness (postural hypotension)
- Low blood pressure (hypotension)
- Physical abnormality of the penis, such as severe curvature, scarring or Peyronie’s disease
- Uncontrolled high blood pressure (hypertension)
- Not to be used in
- Conditions in which sexual activity is not advisable, for example severe heart disorders
- People who have recently had a heart attack
- Severe angina not controlled by medical treatment (severe unstable angina)
- Severe heart failure
- Very low blood pressure (severe hypotension)
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
What are the drug side effects symptoms?
Medicines and their possible side effects can affect individual people in different ways. The following are some symptoms of the side effects that are known to be associated with this medicine. Because a side effect symptoms is stated here, it does not mean that all people using this medicine will experience that or any side effect.
- Mouth ulcers
- Inflammation of the throat (pharyngitis)
- Alteration in taste
- Sleepiness (somnolence)
- Inflammation of the lining of the nose (rhinitis) causing a blocked or runny nose
- Fainting (syncope)
The medication side effects listed above may not include all of the side effects reported by the drug’s manufacturer.
For more information about any other possible risks associated with this medicine, please read the reference information provided with the medicine or consult your doctor or pharmacist.
Interactions Problems: How can this drug affect other medicines?
Apomorphine pills can be taken by men taking nitrate medications, but the combination may cause dizziness. Nitrate medications include the following problems:
– glyceryl trinitrate
– isosorbide mononitrate
– isosorbide dinitrate
– amyl nitrate, also known as “poppers”.
These pills can be taken safely with the antisickness medicines domperidone, ondansetron and prochlorperazine, but other antisickness medicines are not recommended as they have not yet been studied with this medicine.
These pills should not be taken with other medicines that affect dopamine activity in the brain and nervous system (dopamine agonists or antagonists). These medicines include the following:
– certain treatments for Parkinson’s disease, eg bromocriptine, cabergoline, apomorphine, amantadine, levodopa, entacapone, pergolide, lisuride, pramiprexole, ropinirole, selegiline.
– antipsychotic medicines.
If this medicine is taken with alcohol there is an increased risk of a drop in blood pressure. In addition, alcohol can impair sexual performance.
It is recommended that apomorphine should not be taken with other treatments for genital erectile dysfunction.
Uprima sublingual tablets
Main Use Active Ingredient Manufacturer
Impotence Apomorphine hydrochloride (sublingual tablets) by Abbott Labs
What the experts say
“Since generic drugs generally sell for less than brand name drugs, many people falsely believe that generics must be inferior to brand-name products. Generic drugs contain exactly the same active ingredients as the brand-name drugs and are just as safe and effective.”
Doug Sporn, Director
FDA Office of Generic Drugs
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